Imdur

Definition

Imdur is a brand name for isosorbide mononitrate, a medication used to treat chest pain (angina). It belongs to a class of medications called nitrates. Imdur works by relaxing and widening blood vessels, which increases blood flow to the heart and reduces the workload on the heart.

Indications

Imdur is indicated for the prevention of angina pectoris due to coronary artery disease. It is not indicated for the treatment of acute anginal attacks.

Imdur may be used alone or in combination with other antianginal medications, such as beta-blockers, calcium channel blockers, or ranolazine.

Imdur is not indicated for the treatment of heart failure or other cardiovascular conditions.

Imdur is not indicated for the prevention of myocardial infarction or stroke.

Imdur is not indicated for the treatment of hypertension.

Imdur is not indicated for the treatment of erectile dysfunction.

Imdur is not indicated for the treatment of any other condition.

Imdur should be used only under the supervision of a physician who is experienced in the treatment of angina pectoris.

Dosage

The recommended starting dose of Imdur is 30 mg once daily, taken at least 1 hour before or 2 hours after a meal. The dose may be increased to 60 mg once daily or 30 mg twice daily, as needed, to achieve an optimal response. The maximum recommended dose is 120 mg per day.

Imdur should be taken at the same time each day to maintain a constant blood level of the medication.

Imdur tablets should be swallowed whole with a glass of water. Do not crush, chew, or break the tablets.

Imdur may be taken with or without food. However, if Imdur is taken with food, the absorption of the medication may be delayed.

If a dose of Imdur is missed, it should be taken as soon as possible. However, if it is almost time for the next dose, the missed dose should be skipped and the regular dosing schedule should be resumed.

Imdur should not be stopped suddenly. If Imdur is stopped suddenly, it may cause angina to worsen.

The dosage of Imdur should be adjusted by a physician who is experienced in the treatment of angina pectoris.

Administration

Imdur tablets should be swallowed whole with a glass of water. Do not crush, chew, or break the tablets.

Imdur may be taken with or without food. However, if Imdur is taken with food, the absorption of the medication may be delayed.

Imdur should be taken at the same time each day to maintain a constant blood level of the medication.

The usual starting dose of Imdur is 30 mg once daily, taken at least 1 hour before or 2 hours after a meal. The dose may be increased to 60 mg once daily or 30 mg twice daily, as needed, to achieve an optimal response. The maximum recommended dose is 120 mg per day.

Imdur should be used only under the supervision of a physician who is experienced in the treatment of angina pectoris.

If a dose of Imdur is missed, it should be taken as soon as possible. However, if it is almost time for the next dose, the missed dose should be skipped and the regular dosing schedule should be resumed.

Imdur should not be stopped suddenly. If Imdur is stopped suddenly, it may cause angina to worsen.

The dosage of Imdur should be adjusted by a physician who is experienced in the treatment of angina pectoris.

Contraindications

Imdur is contraindicated in patients with the following conditions⁚

• Hypersensitivity to isosorbide mononitrate or any of the other ingredients in Imdur
• Severe hypotension (blood pressure below 90/60 mmHg)
• Recent myocardial infarction (within 48 hours)
• Unstable angina
• Severe aortic stenosis
• Hypertrophic cardiomyopathy
• Constrictive pericarditis
• Tamponade
• Pregnancy
• Lactation

Imdur should be used with caution in patients with the following conditions⁚

• Hepatic impairment
• Renal impairment
• Thyroid disease
• Glaucoma
• Anemia
• Hypovolemia

Overdosage

An overdose of Imdur can cause severe hypotension, which can lead to dizziness, lightheadedness, fainting, and other symptoms. In severe cases, an overdose of Imdur can be fatal.

If an overdose of Imdur is suspected, the patient should be taken to the nearest emergency room immediately.

The treatment of an overdose of Imdur includes supportive measures, such as intravenous fluids and vasopressors, to maintain blood pressure. In severe cases, mechanical ventilation may be necessary.

The following symptoms may indicate an overdose of Imdur⁚

• Severe hypotension
• Dizziness
• Lightheadedness
• Fainting
• Nausea
• Vomiting
• Diarrhea
• Headache
• Flushing
• Blurred vision
• Confusion
• Seizures
• Coma

If you experience any of these symptoms, seek medical attention immediately.

Drug Interactions

Imdur may interact with other medications, including⁚

• Antihypertensive medications, such as ACE inhibitors, angiotensin II receptor blockers, beta-blockers, and calcium channel blockers
• Diuretics
• Nitrates
• Phosphodiesterase-5 inhibitors, such as sildenafil, tadalafil, and vardenafil
• Alcohol

These interactions may increase the risk of hypotension, headache, flushing, and other adverse reactions.

Patients should be advised to inform their physician about all medications they are taking, including prescription and over-the-counter medications, vitamins, and herbal supplements.

Imdur may also interact with certain foods, such as grapefruit juice. Grapefruit juice can increase the levels of Imdur in the blood, which may increase the risk of adverse reactions.

Patients should be advised to avoid grapefruit juice while taking Imdur.

Pharmacology

Imdur is a nitrate that is used to prevent angina pectoris. Nitrates work by relaxing and widening blood vessels, which increases blood flow to the heart and reduces the workload on the heart.

Imdur is absorbed from the gastrointestinal tract after oral administration. The bioavailability of Imdur is about 20%. Imdur is metabolized in the liver and excreted in the urine.

The onset of action of Imdur is within 30 minutes. The duration of action of Imdur is about 6-8 hours.

Imdur is effective in preventing angina pectoris. Imdur has been shown to reduce the frequency and severity of angina attacks, and to improve exercise tolerance.

Imdur is generally well tolerated. The most common adverse reactions to Imdur are headache, flushing, and nausea.

Pharmacokinetics

Imdur is absorbed from the gastrointestinal tract after oral administration. The bioavailability of Imdur is about 20%. Imdur is metabolized in the liver and excreted in the urine.

The peak plasma concentration of Imdur occurs within 1 hour after oral administration.

The half-life of Imdur is about 4 hours.

Imdur is highly bound to plasma proteins.

Imdur is not significantly affected by renal impairment.

Imdur is not significantly affected by hepatic impairment.

Imdur is not significantly affected by age.

Patient Information

Imdur is a medication used to prevent chest pain (angina). It works by relaxing and widening blood vessels, which increases blood flow to the heart.

Imdur is taken by mouth, usually once or twice a day. It is important to take Imdur at the same time each day to maintain a constant level of medication in the blood.

Imdur may cause side effects, such as headache, flushing, and nausea. These side effects are usually mild and go away after a few days.

Imdur should not be taken by people who are allergic to it or to other nitrates.

Availability

Imdur is available as a generic medication and as a brand-name medication. The generic medication is available in both tablet and capsule form. The brand-name medication is available in tablet form only.

Imdur is available in the following strengths⁚

• 30 mg
• 60 mg
• 120 mg

Imdur is available at most pharmacies.

Imdur is also available online. However, patients should only purchase Imdur from reputable online pharmacies.

Pricing

The price of Imdur varies depending on the dosage and quantity prescribed. The average price for a 30-day supply of Imdur is between $30 and $60.

Imdur is available as a generic medication and as a brand-name medication. The generic medication is typically less expensive than the brand-name medication.

Patients may be able to save money on Imdur by using a prescription discount card.

Imdur Cost

The cost of Imdur varies depending on the dosage and quantity prescribed. The average price for a 30-day supply of Imdur is between $30 and $60.

Imdur is available as a generic medication and as a brand-name medication. The generic medication is typically less expensive than the brand-name medication.

The following are some tips for saving money on Imdur⁚

• Use a prescription discount card.
• Ask your doctor about generic Imdur.
• Buy Imdur in bulk.
• Shop around for the best price.

If you have difficulty affording Imdur, you may be able to get help from a patient assistance program.

Generic Availability

Imdur is available as a generic medication. The generic medication is called isosorbide mononitrate.

Generic medications are typically less expensive than brand-name medications. In fact, generic medications are required to contain the same active ingredients as brand-name medications.

There are no significant differences between Imdur and generic isosorbide mononitrate. Both medications are equally effective and safe.

Patients who are looking to save money on Imdur may want to consider asking their doctor about generic isosorbide mononitrate.

International Price Comparison

The price of Imdur varies from country to country. In general, Imdur is less expensive in developing countries than in developed countries.

The following table shows the average price of Imdur in different countries⁚

Country	Average Price
United States	$30-$60
Canada	$40-$70
United Kingdom	£20-£40
Germany	€30-€50
France	€35-€55
India	₹200-₹400
Mexico	$20-$40
Brazil	R$50-R$100

It is important to note that these prices are only averages. The actual price of Imdur may vary depending on the dosage, quantity, and pharmacy.

Manufacturer

Imdur is manufactured by Pfizer Inc.

Pfizer Inc. is a global pharmaceutical company that develops, manufactures, and markets a wide range of prescription and over-the-counter medications.

Pfizer Inc. is headquartered in New York City, New York. The company has operations in more than 150 countries.

Pfizer Inc. is one of the largest pharmaceutical companies in the world. The company's products are used by millions of people around the globe.

Pfizer Inc. is committed to providing high-quality, affordable medications to patients around the world.

Disclaimer

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The information on this website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

If you think you may have a medical emergency, call your doctor or 911 immediately. Reliance on any information provided on this website is solely at your own risk.